Publications
    • Lin KN, Fang SH*, Cai BL, Huang XQ, Zhang XY, Lu YB, Zhang WP, Wei EQ. ERK/Egr-1 signaling pathway is involved in CysLT2 receptor-mediated IL-8 production in HEK293 cells. Eur J Cell Biol. 93(7):278-288, 2014,

    • Fang, San-Hua, Lin, Ka-Na, Huang, Xue-Qin, Lu, Yun-Bi, Zhang, Wei-Ping Wei, Er-Qing*. Nuclear translocation of cysteinyl leukotriene receptor 1 is involved in oxygen-glucose deprivation-induced damage to endothelial cells.  Acta Pharmacol Sin. 2012 Dec;33(12):1511-7.

    • Liu, L. Y. , Wang, F., Zhang, X. Y., Huang, P., Lu, Y. B., Wei, E. Q., Zhang, W. P*. Nicotinamide phosphoribosyltransferase may be involved in age-related brain diseases. PLoS One. 2012;7(10):e44933. doi: 10.1371/journal. pone. 0044933.  Epub 2012 Oct 11

    • Shi QJ, Xiao L, Zhao B, Zhang XY, Wang XR, Xu DM, Yu SY, Fang SH, Lu YB, Zhang WP, Sa XY, Wei EQ*. Intracerebroventricular injection of HAMI 3379, a selective cysteinyl leukotriene receptor 2 antagonist, protects against acute brain injury after focal cerebral ischemia in rats. Brain Res.2012 Nov 12;1484:57-67.

    • Xue-Qin Huang, Xia-Yan Zhang, Xiao-Rong Wang, Shu-Ying Yu, San-Hua Fang, Yun-Bi Lu, Wei-Ping Zhang, Er-Qing Wei*. Transforming growth factor b1-induced astrocyte migration is mediated by activating 5-lipoxygenase and cysteinyl leukotriene receptor 1. Journal  of Neuroinflammation. 2012 Jun 26;9:145.

    • Shi WZ, Qi LL, Fang SH, Lu YB, Zhang WP, Wei EQ*. Aggravated chronic brain injury after focal cerebral ischemia in aquaporin-4-deficient mice. Neurosci Lett. 2012 Jun 27;520(1):121-5.

    • Zhang LY, Liu LY, Qie LL, Ling KN, Xu LH, Wang F, Fang SH, Lu YB, Hu H, Wei EQ, Zhang WP*. Anti-proliferation effect of APO866 on C6 glioblastoma cells by inhibiting nicotinamide phosphoribosyltransferase. Eur J Pharmacol. 2012 Jan 15;674(2-3):163-70.

    • Shi WZ, Zhao CZ, Zhao B, Zheng XL, Fang SH, Lu YB, Zhang WP, Chen Z, Wei EQ*. Aquaporin-4 deficiency attenuates acute lesions but aggravates delayed lesions and microgliosis after cryoinjury to mouse brain. Neurosci Bull. 2012 Feb;28(1):61-8.

    • Zhao B, Zhao CZ, Zhang XY, Huang XQ, Shi WZ, Fang SH, Lu YB, Zhang WP, Xia Q, Wei EQ*. The new P2Y-like receptor G protein-coupled receptor 17 mediates acute neuronal injury and late microgliosis after focal cerebral ischemia in rats.  Neuroscience. 2012 Jan 27;202:42-57.

    • Huang XJ, Li CT, Zhang WP, Lu YB, Fang SH, Wei EQ (2008) Dihydroartemisinin potentiates the cytotoxic effect of temozolomide in rat C6 glioma cells. Pharmacology,82(1):1-9.

    • Huang XJ, Zhang WP, Li CT, Shi WZ, Fang SH, Lu YB, Chen Z, Wei EQ (2008) Activation of CysLT receptors induces astrocyte proliferation and death after oxygen-glucose deprivation. Glia,56(1):27-37.

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      Yuan YM, Fang SH, Qian XD, Liu LY, Xu LH, Shi WZ, Zhang LH, Lu YB, Zhang WP, Wei EQ (2009) Leukotriene D4 stimulates the migration but not proliferation of endothelial cells mediated by the cysteinyl leukotriene cyslt(1) receptor via the extracellular signal-regulated kinase pathway. J Pharmacol Sci, 109(2):285-92.

    •  Fang SH, Yuan YM, Peng F, Li CT, Zhang LH, Lu YB, Zhang WP, Wei EQ (2009) Pranlukast attenuates ischemia-like injury in endothelial cells via inhibiting reactive oxygen species production and nuclear factor-kappaB activation. J Cardiovasc Pharmacol,53(1):77-85.

    • Li CT, Zhang WP, Lu YB, Fang SH, Yuan YM, Qi LL, Zhang LH, Huang XJ, Zhang L, Chen Z, Wei EQ (2009) Oxygen-glucose deprivation activates 5-lipoxygenase mediated by oxidative stress through the p38 mitogen-activated protein kinase pathway in PC12 cells. J Neurosci Res,87(4):991-1001.

    • Li CT, Zhang WP, Fang SH, Lu YB, Zhang LH, Qi LL, Huang XQ, Huang XJ, Wei EQ (2010) Baicalin attenuates oxygen-glucose deprivation-induced injury by inhibiting oxidative stress-mediated 5-lipoxygenase activation in PC12 cells. Acta Pharmacol Sin,31(2):137-44.

    • Chu LS, Fang SH, Zhou Y, Yin YJ, Chen WY, Li JH, Sun J, Wang ML, Zhang WP, Wei EQ (2010) Minocycline inhibits 5-lipoxygenase expression and accelerates functional recovery in chronic phase of focal cerebral ischemia in rats. Life Sci,30;86(5-6):170-7.

    • Zhao CZ, Zhao B, Zhang XY, Huang XQ, Shi WZ, Liu HL, Fang SH, Lu YB, Zhang WP, Tang FD, Wei EQ (2011) Cysteinyl leukotriene receptor 2 is spatiotemporally involved in neuron injury, astrocytosis and microgliosis after focal cerebral ischemia in rats. Neuroscience. 25;189:1-11.

    • Rui Z, Fang SH, Lin KN, Huang XQ, Lu YB, Zhang WP, Wei EQ (2011) Pranlukast Attenuates Hydrogen Peroxide-induced Necrosis in Endothelial Cells by Inhibiting Oxygen Reactive Species-mediated Collapse of Mitochondrial Membrane Potential. J Cardiovasc Pharmacol,57(4):479-88.

    •  Zhao R, Shi WZ, Zhang YM, Fang SH, Wei EQ (2011) Montelukast, a cysteinyl leukotriene receptor-1 antagonist, attenuates chronic brain injury after focal cerebral ischaemia in mice and rats. J Pharm Pharmacol,63(4):550-7.

    • Qi LL, Fang SH, Shi WZ, Huang XQ, Zhang XY, Lu YB, Zhang WP, Wei EQ (2011) CysLT2 receptor-mediated AQP4 up-regulation is involved in ischemic-like injury through activation of ERK and p38 MAPK in rat astrocytes. Life Sci,88(1-2):50-6.

    • Lu YB, Iandiev I, Hollborn M, K?rber N, Ulbricht E, Hirrlinger PG, Pannicke T, Wei EQ, Bringmann A, Wolburg H, Wilhelmsson U, Pekny M, Wiedemann P, Reichenbach A, K?s JA (2011) Reactive glial cells: increased stiffness correlates with increased intermediate filament expression. FASEB J,25(2):624-31.