Featured Publications

1. Zhong WX, Wang YB, Peng L, Ge XZ, Zhang J, Liu SS, Zhang XN, Xu ZH, Chen Z, and Luo JH. 2012. Lanthionine synthetase C-like protein 1 interacts with and inhibits cystathionine-synthase: A target for neuronal antioxidant defense. J Biol Chem.287:34189–201 
2. Yu-bin Wang, Jie-jie Wang, Shao-hua Wang, Shuang-Shuang Liu, Jing-yuan Cao, Xiao-ming Li, Shuang Qiu, and Jian-hong Luo. 2012. Adaptor Protein APPL1 Couples Synaptic NMDA Receptor with Neuronal Prosurvival Phosphatidylinositol 3-Kinase/Akt Pathway. The Journal of Neuroscience, 2012, 32(35): 11919–11929.
3. Zhong K, Wu DC, Jin MM, Xu ZH, Wang Y, Hou WW, Li XM, Zhang SH, Chen Z. Wide therapeutic time-window of low-frequency stimulation at the subiculum for temporal lobe epilepsy treatment in rats. Neurobiol Dis. 2012;48(1):20-26.
4. Shan L, Liu CQ, Balesar R, Hofman MA, Bao AM, Swaab DF .2012.Neuronal histamine production remains unaltered in Parkinson's disease despite the accumulation of Lewy bodies and Lewy neurites in the tuberomamillary nucleus. Neurobiol Aging, 33(7):1343–1344. 
5. Shan L, Bossers K, Luchetti S, Balesar R, Lethbridge N, Chazot PL, Bao AM, Swaab DF .2012.Alterations in the histaminergic system in the substantia nigra and striatum of Parkinson's patients: a postmortem study. Neurobiol Aging, 33(7):1488.e1–1488.e13. 
6. Shan L, Bossers K, Unmehopa U, Bao AM, Swaab DF (2012) Alterations in the histaminergic system in Alzheimer’s disease: a postmortem study. Neurobiol Aging, 33(11):2585-2598. 
7. Shan L, Hofman MA, van Wamelen DJ, Van Someren EJW, Bao AM, Swaab DF (2012) Diurnal fluctuation in histidine decarboxylase expression, the rate limiting enzyme for histamine production, and its disorder in neurodegenerative diseases. Sleep, 35(5):713-715. 
8. Zhou YD, Zhang D, Ozkaynak E, Wang X, Kasper EM, Leguern E, Baulac S, Anderson MP .2012.Epilepsy gene LGI1 regulates postnatal developmental remodeling of retinogeniculate synapses.  Journal of Neuroscience, 32: 903-910.
9. Y Dou, HJ Wu, HQ Li, S Qin, HF Lou, QM Luo, Duan S, Microglia Migration Mediated by ATP-Induced ATP Release from Lysosome, Cell Res, 2012 22:1022-1033
10. Zhu B, Xu D, Deng X, Chen Q, Huang Y, Peng H, Li Y, Jia B, Thoreson WB, Ding W, Ding J, Zhao L, Wang Y, Wavrin KL, Duan S, Zheng J. CXCL12 enhances human neural progenitor cell survival through a CXCR7- and CXCR4-mediated endocytotic signaling pathway. Stem Cells. 2012, 30:2571-2583

Publications

1. Wu ZY, Zhu LJ, Zou N, Bombek LK, Shao CY, Wang N, Wang XX, Liang L, Xia J, Rupnik M, Shen Y. AMPA receptors regulate exocytosis and insulin release in pancreatic β cells. Traffic. 2012 Aug;13(8):1124-1139.
2. Wang DJ, Yang D, Su LD, Xie YJ, Zhou L, Sun CL, Wang Y, Wang XX, Zhou L, Shen Y. Cytosolic Phospholipase A2 alpha/arachidonic acid signaling mediates depolarization-induced suppression of excitation in the cerebellum. PLoS One. 2012;7(8):e41499.
3. Zhu J, Shao CY, Yang W, Zhang XM, Wu ZY, Zhou L, Wang XX, Li YH, Xia J, Luo JH, Shen Y.  Chronic zinc exposure decreases the surface expression of NR2A-containing NMDA receptors in cultured hippocampal neurons. PLoS One. 2012;7(9):e46012.
4. Li Q, Zhou L,Shen Y. Recent research progresses of transferrin receptor 1 in central nervous system. Sheng Li Ke Xue Jin Zhan. 2012 Jun; 43(3):188-92. Chinese.
5. Wagner KV, Marinescu D, Hartmann J, Wang XD, Labermaier C, Scharf SH, Liebl C, Uhr M, Holsboer F, Müller MB, Schmidt MV .2012. Differences in FKBP51 regulation following chronic social defeat stress correlate with individual stress sensitivity: influence of paroxetine treatment. Neuropsychopharmacology 37, 2797-2808.
6. Hartmann J, Wagner KV, Dedic N, Marinescu D, Scharf SH, Wang XD, Deussing JM, Hausch F, Rein T, Schmidt U, Holsboer F, Müller MB, Schmidt MV.2012. Fkbp52 heterozygosity alters behavioral, endocrine and neurogenetic parameters under basal and chronic stress conditions in mice. Psychoneuroendocrinology 37, 2009-2021.
7. Hartmann J, Wagner KV, Liebl C, Scharf SH, Wang XD, Wolf M, Hausch F, Rein T, Schmidt U, Touma C, Cheung-Flynn J, Cox MB, Smith DF, Holsboer F, Müller MB, Schmidt MV.2012. The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress. Neuropharmacology 62, 332-339
8. Cai LQ, Chen WZ, Shen YD, Wang XL, Wei LL, Zhang YC, Wang W, Chen W.2012. Recognition   of  facial  expressions of emotion in  panic disorder. Psychopathology, 45(5):294-299.
9. Wang L, Dai W, Su Y, Wang G, Tan Y, Jin Z, Zeng Y, Yu X, Chen W, Wang X, Si T.2012. Amplitude of low-frequency oscillations in first-episode, treatment-naive patients with major depressive disorder: a resting-state functional MRI study. PLoS One 7, e48658.
10. Wang XD, Labermaier C, Holsboer F, Wurst W, Deussing JM, Müller MB, Schmidt MV* (2012). Early-life stress-induced anxiety-related behavior in adult mice partially requires forebrain corticotropin-releasing hormone receptor 1. European Journal of Neuroscience 36, 2360-2367.
11. Fang M, Wang J, Zhang X, Geng Y, Hu Z, Rudd JA, Ling S, Chen W, Han S .2012. The miR-124  regulates  the  expression of BACE1/β-secretase correlated with cell death in Alzheimer's disease.toxicology letters. 209(1):94-105.
12.  Wang L, Dai W, Su Y, Wang G, Tan Y, Jin Z, Zeng Y, Yu X, Chen W, Wang X, Si T (2012) Amplitude of low-frequency oscillations in first-episode, treatment-naive patients with major depressive disorder: a resting-state functional MRI study. PLoS One. 7(10):e48658.
13. Geng Y, Fang MR, Wang J, Hu ZY, Han S , Rudd JA, Yew DT, Chen W.2012. Triptolide down-regulates COX-2 expression and PGE2 release by suppressing the activity of NF-κB and MAPKs in LPS-treated PC12 cells. phytotherapy research, 26(3): 337-343 .
14. Huan Ma, Samuel Cohen, Boxing Li, Richard W. Tsien*. Exploring the dominant role of Cav1 channels in signaling to the nucleus. Biosci Rep. 2012 Oct 23:97-101.
15. Damian G. Wheeler, Rachel D. Groth, Huan Ma1, Curtis F. Barrett, Scott F. Owen, Parsa Safa, Richard W. Tsien. Specific calcium channel types engage different modes of Ca2+ signaling to control CREB phosphorylation and gene expression.Cell, Volume 149, Issue 5, 25 May 2012, Pages 1112–1124.
16. Li XY, Chen T, Descalzi G, Koga K, Qiu S, Zhuo M. Characterization of neuronal intrinsic properties and synaptic transmission in layer I of anterior cingulate cortex from adult mice, Mol.Pain.2012 8:53.
17. Close J, Xu H, De Marco Garcia N, Batista-Brito R, Rossignol E, Rudy B, Fishell G.2012. Satb1 is an activity-modulated transcription factor required for the terminal differentiation and connectivity of MGE-derived cortical interneurons. The Journal of Neuroscience 32:17690-17705.
18. Eun Chan Park, Piya Ghose, Zhiyong Shao, Qi Ye, Lijun Kang, X Z Shawn Xu, Jo Anne Powell-Coffman & Christopher Rongo (2012). Hypoxia regulates glutamate receptor trafficking through an HIF-independent mechanism. EMBO J  2012 (1)，1-15.
19. Li L, Huangfu L, Chai H, He W, Song H, Zou XH, Wang W.2012.Development of a Functional and Emotional Measure of Dysmenorrhea (FEMD) in Chinese university women. Health Care for Women International, 33: 97-108.
20. He W, Chai H, Chen W, Zhang J, Xu Y, Zhu J, Wang W.2012.Facial emotion triggered cerebral potentials in treatment-resistant depression and borderline personality disorder patients of both genders. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 37: 121-127.
21. Liang W, Zhang Y, Li H, Chu J, Qin Z, He W, Lou L, Li Z, Zou X, Wang W.2012.Personality and primary dysmenorrhea: a study using a five-factor model in Chinese university women. Archives of Neuropsychiatry, 49, 92-5.
22. Chen W, Yu J, Zhu J, Chai H, He W, Wang W.2012.Personality characteristics in male sufferers from chronic tension-type and cervicogenic headaches. Journal of Clinical Neurology, 8(1),69-74.
23. Cai L, Chen W, Shen Y, Wang X, Wei L, Zhang Y, Wang W, Chen W.2012. Recognition of facial expressions of emotion in panic disorder. Psychopathology, 45(5), 294-299..
24. Fang Q, Chen Z. Increased asynchronous GABA release causes more inhibition in human epileptic brain? Acta Pharmacol Sin. 2012 Jul;33(7):859-860.
25. Hu WW, Fang Q, Xu ZH, Yan HJ, He P, Zhong K, Fan YY, Yang Y, Zhang XN, Zhang CY, Ohtsu H, Xu TL, Chen Z. Chronic H1-Antihistamine treatment increases seizure susceptibility after withdrawal by impairing glutamine synthetase. CNS Neurosci Ther. 2012;18(8):683-690.
26. Xu ZH, Wang Y, Jin MM, Yue JX, Xu CL, Ying XY, Wu DC, Zhang SH, Chen Z. Polarity-dependent effect of low-frequency stimulation on amygdaloid kindling in rats. Brain Stimul. 2012,May 16
27. Ma J, Xiong JY, Hou WW, Yan HJ, Sun Y, Huang SW, Jin L, Wang Y, Hu WW, Chen Z. Protective effect of carnosine on subcortical ischemic vascular dementia in mice. CNS Neurosci Ther. 2012 ,18(9):745-753.
28. Xu J, Li W, Chen XY, Jiang DY, Zhang J.M. Early management of intracranial ruptured vertebral dissecting aneurysms. Journal of Zhejiang University. Medical sciences, 2012, 41(1), 93-98. 
29. Bao AM, Ruhé HG,Gao SF, Swaab DF (2012) Neurotransmitters and neuropeptides in depression. Handbook of Clinical Neurology, 107-136. 
30. Swaab DF, Bao AM, Garcia-Falgueras A, Hofman MA, Ishunina1 TA (2012) Sex differences in the human forebrain. Human Nervous System, Chapter 21, 739-758. 
31. Zhao J, Bao AM, Qi XR, Kamphuis W, Luchetti S, Lou JS, Swaab DF (2012) Gene expression of GABA and glutamate pathway markers in the prefrontal cortex of non-suicidal elderly depressed patients. J Affect Disord, 138(3):494-502.
32. R. Fiolka, K. Si, and M. Cui.Complex wavefront corrections for deep tissue focusing using low coherence backscattered light.Optics Express, 20, 16532-16543 (2012).
33. R. Fiolka, K. Si, and M. Cui.Complex wavefront corrections for deep tissue focusing using low coherence backscattered light. Optics Express, 20, 16532-16543 (2012).
34. Minami SS, Sun B, Popat K, Kauppinen T, Pleiss M, Zhou Y, Ward ME, Floreanig P, Mucke l, Desai T, Gan L. Selective targeting of microglia by quantum dots. J Neuroinflammation 2012, 9(1):22.
35. Chen Xuequn, Kong Fanping, Zhao Yang, Du Jizeng High-altitude hypoxia induces disorder of the brain-endocrine-immune network through activation of corticotropin-releasing factor and its type-1 receptors. Chin J Appl Physiol, 2012, 28(6) 482-487.
36. Minami SS, Sun B, Popat K, Kauppinen T, Pleiss M, Zhou Y, Ward ME, Floreanig P, Mucke l, Desai T, Gan L. Selective targeting of microglia by quantum dots.J Neuroinflammation 2012, 9(1):22.
37. Wang C, Sun B, Zhou Y, Grubb A, Gan L. Cathepsin B degrades amyloid-β in mice expressing wildtype human amyloid precursor protein.J Biol Chem 2012, 287(47):39834-39841.
38. He G, Hu J, Li T, Ma X, Meng J, Jia M, Lu J, Ohtsu H, Chen Z, Luo X. The arrhythmogenic effect of sympathetic histamine in mouse hearts subjected to acute ischemia. Mol Med. 2012;18(1):1-9.
39. Zhu J, Feng F, Ni K, Zheng Y, Zhang JM. Four subtypes of motor neurons exhibiting mutually exclusive firing patterns in the spinal ventral horn. Neuroscience letters, 2012, 525(2), 163-167 
40. Hu WW, Yang Y, Wang Z, Shen Z, Zhang XN, Wang GH, Chen Z. H1-antihistamines induce vacuolation in astrocytes through macroautophagy. Toxicol Appl Pharmacol, 2012;260 (2):115-123.
41. Shi WZ, Zhao CZ, Zhao B, Zheng XL, Fang SH, Lu YB, Zhang WP, Chen Z, Wei EQ. Aquaporin-4 deficiency attenuates acute lesions but aggravates delayed lesions and microgliosis after cryoinjury to mouse brain. Neurosci Bull. 2012;28(1):61-68.
42. Hong Y, Guo, SX, Chen S, Sun CR, Zhang JM, Sun X; Beneficial effect of hydrogen-rich saline on cerebral vasospasm after experimental subarachnoid hemorrhage in rats. Journal of neuroscience research, 2012, 90(8), 1670-1680 
43. Chai H, Chen W, Zhu J, Xu Y, Lou L, Yang T, He W, Wang W.2012. Processing of facial expressions of emotion in healthy volunteers: an exploration with event-related potentials and personality traits. Neurophysiologie Clinique,42: 369-375.
44.  Chai H, Xu S, Zhu J, Chen W, Xu Y, He W, Wang W.2012. Further evidence for the fifth disordered personality higher-trait: a correlation study using normal and disordered personality measures. Psychiatry Research,200: 444-449.
45. Zhu J, Xu Y, Huang J, Yeow CD, Wang W.2012.Traditional and online consumers in China: A preliminary study of their personality traits and decision-making styles.Psychiatria Danubina,24: 392-399.
46. Yu S, Zhu J, Xu Y, Zheng L, Chai H, He W, Liu W, Li HC, Wang W.2012. Processing environmental stimuli in paranoid schizophrenia: recognizing facial emotions and performing executive functions.  Biomedical and Environmental Sciences,25: 697-705.
47. Zhu XD, Chen JS, Zhou F, Liu QC, Chen G., Zhang JM, Relationship between plasma high mobility group box-1 protein levels and clinical outcomes of aneurysmal subarachnoid hemorrhage. Journal of neuroinflammation, 2012, 9, 194 
48. Hu WW, Chen Z. Role of histamine and its receptors in cerebral ischemia. ACS Chem Neurosci. 2012;3 (4):238-247.
49. Wang RR, Zhang XN, Zhang JX, Fan YY, Shen Y, Hu WW, Chen Z. Oxygen-glucose deprivation induced glial scar-like change in astrocytes. PLoS One. 2012;7(5):e37574.
50. Wang Peirong, Feng Bin, Liu Lanying, Chen Jiong, Chen Zhen, Shen Yuedi, Chen Wei(2012).The primary application of mood disorder questionnaire for screening for bipolar disorder out of depressive disorder. Chinese Journal of Psychiatry. 45(3):150-153.