2017

Location : homepage  RESEARCH  Publication  2017

    Featured Publications

    1. Zhou T, Zhu H, Fan Z, Wang F, Chen Y, Liang H, Yang Z, Zhang L, Lin L, Zhan Y, Wang Z, Hu H. History of winning remodels thalamo-PFC circuit to reinforce social dominance. Science, 2017 Jul 14;357(6347):162-168.  

    2. Wei Wan, Zhiyuan You, Yinfeng Xu, Li Zhou, Zhunlv Guan, Chao Peng, Catherine C.L. Wong, Hua Su, Tianhua Zhou, Hongguang Xia, Wei Liu. mTORC1 Phosphorylates Acetyltransferase p300 to Regulate Autophagy and Lipogenesis. Mol Cell, 2017 Oct 19, 68(2), 323-335.    
    3. Yi Wang, Cenglin Xu, Zhenghao Xu, Caihong Ji, Jiao Liang,Ying Wang, Bin Chen, Xiaohua Wu, Feng Gao,Shuang Wang, Yi Guo, Xiaoming Li, Jianhong Luo, Shumin Duan, and Zhong Chen.Depolarized GABAergic Signaling in Subicular Microcircuits Mediates Generalized Seizure in Temporal Lobe Epilepsy. Neuron, 2017 July 5,95, 1–14.   
    4. Tan Z, Liu Y,Xi W,Lou HF, Zhu L,Guo Z,Mei L,Duan S. Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons. Nat Comm ,2017 Jan 27,(8):13772.   
    5. Hu W, Chen Z. The roles of histamine and its receptor ligands in central nervous system disorders: An update. Pharmacol Ther, 2017, Feb 20.pii: S0163-7258(17)30063-3.   
    6. Zhang Q, He Q, Wang J, Fu C, Hu H*. Use of TAI-FISH to visualize neural ensembles activated by multiple stimuli. Nat Protoc, 2017 Dec 14, 13, 118-133. 10.032   
    7. Dong X, Gong Z, Lu Y B, Liu K, Qin L Y, Ran M L, Zhang C L, Liu Z, Zhang W P, and Tang C. Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch. Proc Natl Acad Sci U S A, 2017 Jun 13.   
    8. Shen Z, Zheng Y, Wu J, Chen Y, Wu X, Zhou Y, Yuan Y, Lu S, Jiang L, Qin Z, Chen Z, Hu W, Zhang X. PARK2-dependent mitophagy induced by acidic postconditioning protects against focal cerebral ischemia and extends the reperfusion window. Autophagy, 2017 Mar 4, 13(3): 473-485.  
    9. Yuan Y, Zheng Y, Zhang X, Chen Y, Wu X, Wu J, Shen Z, Jiang L, Wang L, Yang W, Luo J, Qin Z, Hu W, Chen Z*.BNIP3L/NIX-mediated mitophagy protects against ischemic brain injury independent of PARK2. Autophagy. 2017 Oct 3;13(10):1754-1766.
    10. Li JT, Xie XM, Yu JY, Sun YX, Liao XM, Wang XX, Su YA, Liu YJ, Schmidt MV, Wang XD*, Si TM*. Suppressed calbindin levels in hippocampal excitatory neurons mediate stress-induced memory loss. Cell Rep ,2017 Oct 24,21, 891-900.  
    11. Zhai Q, Lai D, Cui P, Zhou R, Chen Q, Hou J, Su Y, Pan L, Ye H, Jing-Wei Zhao*,Fang X*. Selective Activation of Basal Forebrain Cholinergic Neurons Attenuates Polymicrobial Sepsis-Induced Inflammation via the Cholinergic Anti-Inflammatory Pathway. Crit Care Med. 2017 Oct;45(10):e1075-e1082. doi: 10.1097/CCM.0000000000002646.(*共同通讯作者)
    12. Hongguang Xia*, Yuanyuan An, Xincheng Zeng, Jie Wu*. Palladium-catalyzed direct sulfonylation of C-H bonds with the insertion of sulfur dioxide. Chem.Commun. 2017 Nov 21, 53, 12548--12551.  
    13. Bin Zhang, Weiwei Wang, Zhenjie Zhang, Yaling Hu, Fan Meng, Fan Wang, Huifang Lou, Liya Zhu, Roseline Godbout, Shumin Duan, Zhihua Gao*; Alternative Splicing of Disabled-1 Controls Multipolar-to-Bipolar Transition of Migrating Neurons in the Neocortex, Cerebral Cortex, 2017 Aug 22:1-11.
    14. Hu TT, Wang RR, Tang YY, Wu YX, Yu J, Hou WW, Lou GD, Zhou YD, Zhang SH, Chen Z*.TLR4 deficiency abrogated widespread tactile allodynia, but not widespread thermal hyperalgesia and trigeminal neuropathic pain after partial infraorbital nerve transection. Pain. 2017 Nov 3.  
    15. Dai D, Li QC, Zhu QB, Hu SH, Balesar B, Swaab DF, Bao AM*. Direct involvement of androgen receptor in oxytocin gene expression: possible relevance for mood disorders. Neuropsychopharmacology, 2017 Sep;42(10):2064-2071.  
    16. Jiang Q, Gao Y, Wang C, Tao R, Wu Y, Zhan K, Liao M, Lu N, Lu Y, Wilcox C S, Luo J, Jiang L H, Yang W, and Han F. Nitration of TRPM2 as a Molecular Switch Induces Autophagy During Brain Pericyte  Injury. Antioxid Redox Signal, 2017 Mar 14.
    17. Wei Zhou, Jingjing Wang, Kaiyue wang, Bin Huang, Lili Niu, Fei Li, Feiyan Cai, Yan Chen, Xin Liu, Xiaoyan Zhang, Hankui Cheng, Lijun Kang#,  Long Meng# and Hairong Zheng#. Ultrasound neuro-modulation chip: activation of sensory neurons in Caenorhabditis elegans by surface acoustic waves. Lab Chip ,2017 May 16;17(10). 
    18. Wang C, Sun C, Hu Z, Huo X, Yang Y, Liu X, Botchway BO, Davies H, Fang M. Improved Neural Regeneration with Olfactory Ensheathing Cell Inoculated PLGA Scaffolds in Spinal Cord Injury Adult Rats. Neurosignals, 2017 Mar 30;25(1):1-14.  
    19. Xiang M, Jiang Y, Hu Z, Yang Y, Botchway BOA, Fang M. Stimulation of Anxiety-Like Behavior via ERK Pathway by Competitive Serotonin Receptors 2A and 1A in Post-Traumatic Stress Disordered Mice. Neurosignals. 2017 Oct 6;25(1):39-53.
    20. Li Y, Shen XZ, Li L, Zhao TV, Bernstein KE, Johnson AK, Lyden P, Fang J, Shi P. Brain Transforming Growth Factor-β Resists Hypertension Via Regulating Microglial Activation. Stroke, 2017 Jul 11.
    21. Zhou JH , Wang XT , Zhou L , Zhou L , Xu FX , Su LD , Wang H , Jia F , Xu FQ , Chen GQ , De Zeeuw C , Shen Y. Ablation of TFR1 in Purkinje cells inhibits mGlu1 trafficking and impairs motor coordination, but not autistic-like behaviors. J Neurosci. 20 October 2017, 1223-17.
    22. Geng HY, Zhang J, Yang JM, Li Y, Wang N, Ye M, Chen XJ, Lian H, Li XM. Erbb4 Deletion from Medium Spiny Neurons of the Nucleus Accumbens Core Induces Schizophrenia-like Behaviors via Elevated GABAAR α1 Expression. J Neurosci, 2017 Aug 2.
    23. Zhao J, Wang Y, Xu C, Liu K, Wang Y, Chen L, Wu X, Gao F, Guo Y, Zhu J, Wang S, Nishibori M, Chen Z. Therapeutic potential of an anti-high mobility group box-1 monoclonal antibody in epilepsy. Brain Behav Immun,  2017, pii:S0889-1591(17)30024-7.
    24. Yiting Zhou, Jing Zhang, Lu Wang, Ying Chen, Yushan Wan, Yang He, Lei Jiang,Jing Ma, Rujia Liao, Xiangnan Zhang, Liyun Shi, Zhenghong Qin, Yudong Zhou,Zhong Chen* , Weiwei Hu. Interleukin-1b impedes oligodendrocyte progenitor cell recruitment and white matter repair following chronic cerebral hypoperfusion.Brain Behav Immun, 2017; 60 (2017) 93–105.
    25. Qian Q, Zhou D, Liu Q, Pan H, Liu Z, He F, Ji S, Wang D, Bao W, Liu X, Liu Z, Zhang H, Zhang X, Zhang L, Wang M, Xu Y, Huang F, Luo B*, Sun B*. Brain-Specific Ablation of Efr3a Promotes Adult Hippocampal Neurogenesis Via Brain Derived Neurotrophic Factor Pathway. FASEB J, 2017 May, 31(5): 2104-2113.
    26. Zhang B, Xu Y, He W, Wang J, Chai H, Shen C, Zhu Q, Wang W*. Intensity dependence of auditory evoked potentials in primary dysmenorrhea.J Pain. 2017 Nov; 18: 1324-1332.
    27. Mei Han, Wenjuan Zou, Hao Chang, Yong Yu, Haining Zhang, Shitian Li, Hankui Cheng, Guifeng Wei, Yan Chen, Valerie Reinke, Tao Xu#, Lijun Kang#. A systematic RNAi screen reveals a novel role of a spindle assembly checkpoint protein BuGZ in synaptic transmission in C. elegans. Front Mol Neurosci. 2017 May 11; 10: 141. 
    28. Peng L, Yang Q, Xu X, Du Y, Wu Y, Shi X, Xu J, Zhu L, Luo J. Huntingtin-Interacting Protein 1-Related Protein Plays a Critical Role in Dendritic Development and Excitatory Synapse Formation in Hippocampal Neurons.Front Mol Neurosci. 2017 Jun 15;10:186.
    29. Zhang H, Zhang L, Zhou D, He X, Wang D, Pan H, Zhang X, Mei Y, Qian Q, Zheng T, Jones FE, Sun B*. Ablating ErbB4 in PV neurons attenuates synaptic and cognitive deficits in an animal model of Alzheimer's disease. Neurobiol Dis. 2017, 106: 171-180.
    30. Kaida Zhou, Hongguang Xia* and Jie Wu*. Generation of benzosultams via a radical process with the insertion of sulfur dioxide. Org. Chem. Front , 2017, 4, 1121-1124.
    31. Hongguang Xia*, Yuanyuan An,Xincheng Zeng and Jie Wu*. A copper-catalyzed sulfonylative C-H bond functionalization from sulfur dioxide and aryldiazonium tetrafluoroborates. Org. Chem. Front, 2017, in press.
    32. Pan L, Yang J, Yang Q,Wang X, Zhu L, Liu Y, Lou H, Xu C, Shen Y, Wang H. A Critical Period for the Rapid Modification of Synaptic Properties at the VPm Relay Synapse. Front Mol Neurosci,2017 Jul 25; 10:238.
    33. Yang S, Yang F, Zhang B, Lee BH, Li B, Luo, L., Zheng J, and Lai R. A bimodal activation mechanism underlies scorpion toxin-induced pain. Sci Adv, 2017 Aug 2;3(8):e1700810.

     

    Publications 

    1. Wu D, Feng B, Dai Y, Wu X, Chen B, Xu C, Tang Y, Wang K, Zhang S, Wang S, Luo B, Chen Z. Intergenerational Transmission of Enhanced Seizure Susceptibility after Febrile Seizures. EBioMedicine, 2017, 17: 206-215.
    2. Zhu JM, Li KX, Cao SX, Chen XJ, Shen CJ, Zhang Y, Geng HY, Chen BQ, Lian H, Zhang JM, Li XM. Increased NRG1-ErbB4 signaling in human symptomatic epilepsy. Sci Rep, 2017, 7(1): 141.
    3. Jiang H, Zhang Y, Tian K, Wang B, and Han S. Amelioration of experimental autoimmune encephalomyelitis through transplantation of placental derived mesenchymal stem cells. Sci Rep, 2017, 7:41837.
    4. Lu J, Zhao J, Balesar R, Fronczekd R, Zhu QB, Wu XY, Hu SH, Bao AM, Swaab DF. Sexually dimorphic changes of hypocretin (orexin) in depression. EBioMedicine, 18 (2017) 311–319.
    5. Zheng T, Pu J, Chen Y, Mao Y, Guo Z, Pan H, Zhang L, Zhang H, Sun B, Zhang B. Plasma Exosomes Spread and Cluster Around β-Amyloid Plaques in an Animal Model of Alzheimer’s Disease. Front. Aging Neurosci, 2017, 9:12.  
    6. Yu P, Xue X, Zhang J, Hu X, Wu Y, Jiang L H, Jin H, Luo J, Zhang L, Liu Z, and Yang W. Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2. J Gen Physiol, 2017, 149(2):219.
    7. Ke Q, Ye J, Tang S, Wang J, Luo B, Ji F, Zhang X, Yu Y, Cheng X, Li Y.N1366S mutation of human skeletal muscle sodium channel causes paramyotonia congenita. J Physiol,  2017 Sep 20.
    8. Wu XY, Balesar R, Lu J, Farajnia S, Zhu QB, Huang ML, Bao AM, Swaab DF. Increased glutamic acid decarboxylase expression in the hypothalamic suprachiasmatic nucleus in depression. Brain Struct Funct , 2017 Dec;222(9):4079-4088.
    9. Wu JL, He Y, Hrubý R, Balesar R, Qi YJ, Guo L, Ren Z, Zhu QB, Huang ML, Swaab DF, Bao AM. Aromatase changes in depression: a postmortem and animal experimental study. Psychoneuroendocrinology. 2017 Mar;77:56-62.
    10. Lu Y*, Ho CS, Liu X, Chua A. Wang W, McIntyrer RS, Ho RC. Chronic administration of fluoxetine and pro-inflammatory cytokine change in a rat model of depression. PloS One 2017:12:e0186700.
    11. Yan-Ying Fan, Wei-Wei Hu, Fang Nan , Zhong Chen. Postconditioning-induced neuroprotection, mechanisms and applications in cerebral ischemia. Neurochem Int , 107 (2017) 43-56.
    12. Tian KW#, Zhang F#, Jiang H, Wang B, Han S. Role of C16, angiopoietin-1 and regeneration gene protein 2 in attenuating inflammation in experimental autoimmune encephalomyelitis model. J Anat, 2017, 230(1):30-46 医学院TOP期刊
    13. Xu M, Sun P, Zhang Y, Yang CH, Wei X, Ma XX, Yang CR, Ni KM, Zhang YJ, Li XM. DV21 decreases excitability of cortical pyramidal neurons and acts in epilepsy. Sci Rep, 2017 May 10; (1):1701 . 
    14. Chen CX, Huang J, Tu GQ, Lu JT, Xie X, Zhao B, Wu M, Shi QJ, Fang SH, Wei EQ, Zhang WP, Lu YB. NAMPT inhibitor protects ischemic neuronal injury in rat brain  via anti- neuroinflammation. Neuroscience. 2017 May 19;356:193-206.
    15. Wang XX, Li JT, Xie XM, Gu Y, Si TM, Schmidt MV, Wang XD. Nectin-3 modulates the structural plasticity of dentate granule cells and long-term memory. Transl Psychiatry, 2017, 7, e1228.
    16. Li K, Shen S, Ji YT, Li XY, Zhang LS, Wang XD. Melatonin augments the effects of fluoxetine on depression-like behavior and hippocampal BDNF-TrkB signaling. Neurosci Bull, 2017,in press.
    17. Liu X, Zhang Y, Yang Y, Lin J, Huo X, Du X, Botchway BOA, Fang M. Therapeutic Effect of Curcumin and Methylprednisolone in the Rat Spinal Cord Injury. Anat Rec (Hoboken) , 2017 Nov 18.
    18. Du X, Huo X, Yang Y, Hu Z, Botchway BOA, Jiang Y, Fang M. miR-124 downregulates BACE 1 and alters autophagy in APP/PS1 transgenic mice. Toxicol Lett, 2017 Oct 5;280:195-205.
    19. Yang Y, Hu Z, Du X, Davies H, Huo X, Fang M. miR-16 and Fluoxetine Both Reverse Autophagic and Apoptotic Change in Chronic Unpredictable Mild Stress Model Rats. Front Neurosci, 2017 Jul 25;11:428. doi: 10.3389/fnins.2017.00428. eCollection 2017.
    20. Hu Z, Jiang Y, Huo X, Yang Y, Davies H, Botchway BOA, Fang M. Prospective Role of MicroRNAs in Depression. Curr Med Chem,  2017;24(32):3508-3521.
    21. Wang C, Hu Z, Zou Y, Xiang M, Jiang Y, Botchway BOA, Huo X, Du X, Fang M. The post-therapeutic effect of rapamycin in mild traumatic brain-injured rats ensuing in the upregulation of autophagy and mitophagy. Cell Biol Int, 2017 Sep;41(9):1039-1047.
    22. Wang, CX, Ruan, JW, Huang, Y, Hu, ZY, Du, XX, Huo, X, Akinleye, FO, Botchway, BOA, Fang M. Triptolide Promotes the Repair of Spinal Cord Injury by Inhibiting Autophagy in Rats Models. J BIOMATER TISS ENG, Aug 2017. 7; 8: 655-661.
    23. Yang Y#, Fang M#, Du X, Hu Z. Lucky gene 5-HTTLPR and postpartum depression: A systematic review. Neuro Endocrinol Lett. 2017 Oct 6;38(5):316-320.  
    24. Botchway BOA, Moore KM, Akinleye FO, Iyer IC, Fang M. Nutrition: Review on the Possible Treatment for Alzheimer's Disease. J  Alzheimers Dis. 2017, 61(3). doi: 10.3233/JAD-170874.
    25. Zhao W, Gong C, Ouyang Z, Wang P, Wang J, Zhou P, Zheng N, Gong Z. Turns with multiple and single head cast mediate Drosophila larval light avoidance. PLoS One. 2017 Jul 11;12(7):e0181193. doi: 10.1371/journal.pone.0181193.  
    26. Nenggan Zheng, Jun Wen, Risheng Liu, Liangqu Long, Jianhua Dai, Zhefeng Gong.Unsupervised Representation Learning with Long-Term Dynamics for Skeleton Based Action Recognition, AAAI ,2018.
    27. Wu Y, Chen CW, Yang Q, Jiao MF, and Qiu S. Endocytosis of GluN2B-containing NMDA receptors mediates NMDA-induced excitotoxicity in PC12 cells. Molecular Pain, 2017 13:1-13.
    28. Zhang X, Wang D, Pan H, Sun B*. Enhanced Expression of Markers for Astrocytes in the Brain of a Line of GFAP-TK Transgenic Mice. Front Neurosci. 2017, 11:212.
    29. Zheng T, Pu J, Chen Y, Mao Y, Guo Z, Pan H, Zhang L. Zhang H, Sun B*, Zhang B*. Plasma exosomes spread and cluster around β-amyloid plaques in an animal model of Alzheimer's disease. Front Aging Neurosci 2017, 9: 12  
    30. Zheng T, Pu J, Chen Y, Guo Z, Pan H, Zhang L, Zhang H, Sun B*, Zhang B*.Exosomes Secreted from HEK293-APP Swe/Ind Cells Impair the Hippocampal Neurogenesis. Neurotox Res. 2017, 32(1): 82-93.
    31. Ullah R, Su Y, Shen Y, Li C, Xu X, Zhang J, Huang K, Rauf N, He Y, Cheng J, Qin H, Zhou YD*, Fu J*. Postnatal feeding with high-fat diet induces obesity and precocious puberty in C57BL/6J mouse pups: a novel model of obesity and puberty. Front Med. 2017, 11: 266-276.
    32. Zhu Q, Wang J, Shen C, Fan H, Zhang B, Ma G, Lu Y, Wang W*. Brainstem inhibitory reflexes under external emotions in bipolar I and II disorders. BMC Psychiatry. 2017; 17: 224.
    33. Zhang B, Wang J, Zhu Q, Ma G, Shen C, Fan H, Wang W*. Hypnotic susceptibity and affective states in bipolar I and II disorders. BMC Psychiatry 2017; 17: 362.
    34. Wang J, Zhang B, Shen C, Zhang J, Wang W*. Headache symptoms from migraine patients with and without aura through structure-validated self-reports. BMC Neurol. 2017; 17: 193.
    35. Zhang Y, Wang Y, Shen C, Ye Y, Shen S, Zhang B, Wang J, Chen W, Wang W*. Relationship between hypnosis and personality trait in participants with high or low hypnotic susceptibility. Neuropsychiatr Dis Treat,  2017; 13: 1007-1012.  
    36. He W, Zheng Q, Ji Y, Shen C, Zhu Q, Wang W*. Development of a Body Image Concern Scale using both exploratory and confirmatry factor analyses in Chinese university students. Neuropsychiatr Dis Treat,  2017; 13: 1419-1425.
    37. Mao H, Ji Y, Xu Y, Tang G, Yu Z, Xu L, Shen C, Wang W*. Group cognitive-behavioral therapy in insomnia: a cross-sectional case-controlled study. Neuropsychiatr Dis Treat,  2017; 13: 2841-2848.
    38. Zhang Y, Liu J, Wang Y, Huang J, Wei L, Zhang B, Wang W, Chen W*. Personality traits and perception of Mueller-Lyer Illusion in male Chinese military soldiers and university students. Transl Neurosci, 2017; 8: 15-20.  
    39. Zou W, Cheng H, Li S, Yue X, Xue Y, Chen S#, Kang L#. Polymodal Responses in C.elegans Phasmid Neurons Rely on Mulitiple Intracellular and Intercellular Signaling Pathways. Sci Rep. 2017 Feb 14;7:42295.
    40. Sheng Y, Tang L, Kang L, Xiao R. Membrane ion Channels and Receptors in Animal lifespan Modulation. J Cell Physiol. 2017 Jan 25. 
    41. Wu JL, He Y, Hrubý R, Balesar R, Qi YJ, Guo L, Ren Z, Zhu QB, Huang ML, Swaab DF, Bao AM*. Aromatase changes in depression: a postmortem and animal experimental study. Psychoneuroendocrinology, 2017 Mar;77:56-62.
    42. The C. elegans Taste Receptor Homolog LITE-1 Is a Photoreceptor. Gong J, Yuan Y, Ward A, Kang L, Zhang B, Wu Z, Peng J, Feng Z, Liu J, Xu XZS. Cell. 2017 Jan 12;168(1-2):325. 
    43. Shan L, Bao AM, Swaab DF. Changes in Histidine Decarboxylase, Histamine N-Methyltransferase and Histamine Receptors in Neuropsychiatric Disorders. Handb Exp Pharmacol., 2017;241:259-276.