报告题目: The neuronal mechanism of chronic pain, from synaptic transmission to information coding
报 告 人: Xiangyao Li(李相尧), Ph.D.
Principal Investigator/Professor
Lab of Neuronal Circuitry and Disease
Center for Neuron and Disease
Frontier Institute of Science and Technology
Xi'an Jiaotong University
报告时间: 2013年12月3日(周二)上午10:00-11:00
报告地点: 医学院科研楼B502会议室
联 系 人: 孙秉贵 教授
报告摘要:
Chronic pain is a major health issue in human society caused mainly by tissue or nerve injury. The common pathological conditions include spontaneous pain, allodynia and hyperalgesia. Peripheral sensitization and central plasticity are likely to contribute to chronic pain. The long-term change of the synaptic transmission under chronic pain has been studied along the sensory pathway, and PKM zeta has been treated as a new target for chronic pain treatment. And how the enhanced synaptic transmission affects information coding, especially the temporal information coding will be discussed.