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Featured Publications

  1. Tan Z, Liu Y,Xi W,Lou HF, Zhu L,Guo Z,Mei L,Duan S. Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons. Nat Comm ,2017,(8):13772. 

  2. Hu W, Chen Z. The roles of histamine and its receptor ligands in central nervous system disorders: An update. Pharmacol Ther, 2017, Feb 20.pii: S0163-7258(17)30063-3.

  3. Shen Z, Zheng Y, Wu J, Chen Y, Wu X, Zhou Y, Yuan Y, Lu S, Jiang L, Qin Z, Chen Z, Hu W, Zhang X. PARK2-dependent mitophagy induced by acidic postconditioning protects against focal cerebral ischemia and extends the reperfusion window. Autophagy, 2017, 13(3): 473-485.

  4. Wu D, Feng B, Dai Y, Wu X, Chen B, Xu C, Tang Y, Wang K, Zhang S, Wang S, Luo B, Chen Z. Intergenerational Transmission of Enhanced Seizure Susceptibility after Febrile Seizures. EBioMedicine, 2017, 17: 206-215.

  5. Zhao J, Wang Y, Xu C, Liu K, Wang Y, Chen L, Wu X, Gao F, Guo Y, Zhu J, Wang S, Nishibori M, Chen Z. Therapeutic potential of an anti-high mobility group box-1 monoclonal antibody in epilepsy. Brain Behav Immun, 2017, pii:S0889-1591(17)30024-7.  

  6. Geng HY, Zhang J, Yang JM, Li Y, Wang N, Ye M, Chen XJ, Lian H, Li XM. Erbb4 Deletion from Medium Spiny Neurons of the Nucleus Accumbens Core Induces Schizophrenia-like Behaviors via Elevated GABA ARα1 Expression.  J Neurosci, 2017, Revised.

  7. Zhu JM, Li KX, Cao SX, Chen XJ, Shen CJ, Zhang Y, Geng HY, Chen BQ, Lian H, Zhang JM, Li XM. Increased NRG1-ErbB4 signaling in human symptomatic epilepsy. Sci Rep, 2017, 7(1): 141.

  8. Jiang H, Zhang Y, Tian K, Wang B, and Han S. Amelioration of experimental autoimmune encephalomyelitis through transplantation of placental derived mesenchymal stem cells. Sci Rep, 2017, 7:41837.

  9. Jiang Q, Gao Y, Wang C, Tao R, Wu Y, Zhan K, Liao M, Lu N, Lu Y, Wilcox C S, Luo J, Jiang L H, Yang W, and Han F. Nitration of TRPM2 as a Molecular Switch Induces Autophagy During Brain Pericyte  Injury. Antioxid Redox Signal, 2017 Mar 14.

  10. Dong X, Gong Z, Lu Y B, Liu K, Qin L Y, Ran M L, Zhang C L, Liu Z, Zhang W P, and Tang C. Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch. Proc Natl Acad Sci U S A, 2017 Jun 13. 

  11. Yi Wang, Cenglin Xu, Zhenghao Xu, Caihong Ji, Jiao Liang,Ying Wang, Bin Chen, Xiaohua Wu, Feng Gao,Shuang Wang, Yi Guo, Xiaoming Li, Jianhong Luo, Shumin Duan, and Zhong Chen.Depolarized GABAergic Signaling in Subicular Microcircuits Mediates Generalized Seizure in Temporal Lobe Epilepsy. Neuron, 2017 July 5,95, 1–14. 

  12. Li Y, Shen XZ, Li L, Zhao TV, Bernstein KE, Johnson AK, Lyden P, Fang J, Shi P. Brain Transforming Growth Factor-β Resists Hypertension Via Regulating Microglial Activation. Stroke, 2017 Jul 11.

  13. Zhou T, Zhu H, Fan Z, Wang F, Chen Y, Liang H, Yang Z, Zhang L, Lin L, Zhan Y, Wang Z, Hu H. History of winning remodels thalamo-PFC circuit to reinforce social dominance. Science, 2017 Jul 14;357(6347):162-168.

  14. Geng HY, Zhang J, Yang JM, Li Y, Wang N, Ye M, Chen XJ, Lian H, Li XM.Erbb4 Deletion from Medium Spiny Neurons of the Nucleus Accumbens Core Induces Schizophrenia-Like Behaviors via Elevated GABAA Receptor α1 Subunit Expression.J Neurosci, 2017 Aug 2;37(31):7450-7464.

  15. Zhou JH , Wang XT , Zhou L , Zhou L , Xu FX , Su LD , Wang H , Jia F , Xu FQ , Chen GQ , De Zeeuw C , Shen Y .Ablation of TFR1 in Purkinje cells inhibits mGlu1 trafficking and impairs motor coordination, but not autistic-like behaviors. J Neurosci. 20 October 2017, 1223-17



  1. Zheng T, Pu J, Chen Y, Mao Y, Guo Z, Pan H, Zhang L, Zhang H, Sun B, Zhang B. Plasma Exosomes Spread and Cluster Around β-Amyloid Plaques in an Animal Model of Alzheimer's Disease. Front. Aging Neurosci, 2017, 9:12.  

  2. Yu P, Xue X, Zhang J, Hu X, Wu Y, Jiang L H, Jin H, Luo J, Zhang L, Liu Z, and Yang W. Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2. J Gen Physiol, 2017, 149(2):219.

  3. Ke Q, Ye J, Tang S, Wang J, Luo B, Ji F, Zhang X, Yu Y, Cheng X, Li Y.N1366S mutation of human skeletal muscle sodium channel causes paramyotonia congenita. J Physiol. 2017 Sep 20.